A drug may be classified by the chemical type of the active ingredient or by the way it is used to treat a particular condition. Each drug can be classified into one or more drug classes.
Beta-lactamase inhibitors block the activity of beta-lactamase enzymes.
Some species of bacteria produce beta-lactamase enzymes, which cleave the beta-lactam group in antibiotics, such as penicillin, that have a beta-lactam ring in their structure. In doing so the beta-lactamase enzyme inactivates the antibiotic and becomes resistant to that antibiotic. To avoid development of resistance, beta-lactamase inhibitors are administered with the beta-lactam antibiotics so the action of beta-lactamase is inhibited. This tends to widen the spectrum of antibacterial activity.
See also
Medical conditions associated with beta-lactamase inhibitors:
- Appendectomy
- Aspiration Pneumonia
- Bacteremia
- Bacterial Infection
- Bone infection
- Bronchitis
- Deep Neck Infection
- Endometritis
- Epiglottitis
- Febrile Neutropenia
- Intraabdominal Infection
- Joint Infection
- Kidney Infections
- Melioidosis
- Meningitis
- Nosocomial Pneumonia
- Otitis Media
- Pelvic Inflammatory Disease
- Peritonitis
- Pneumonia
- Pneumonia with Cystic Fibrosis
- Septicemia
- Sinusitis
- Skin and Structure Infection
- Skin Infection
- Small Bowel Bacterial Overgrowth
- Strep Throat
- Surgical Prophylaxis
- Upper Respiratory Tract Infection
- Urinary Tract Infection
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